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	Provedor de dados Genet. Mol. Biol. (1) Autor Barbosa,Hélio J. C. (1) Custódio,Fábio L. (1) Dardenne,Laurent E. (1) Palavra-chave Genetic algorithms (1) HP model (1) Protein folding (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2004 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Investigation of the three-dimensional lattice HP protein folding model using a genetic algorithm Genet. Mol. Biol. Custódio,Fábio L.; Barbosa,Hélio J. C.; Dardenne,Laurent E.. An approach to the hydrophobic-polar (HP) protein folding model was developed using a genetic algorithm (GA) to find the optimal structures on a 3D cubic lattice. A modification was introduced to the scoring system of the original model to improve the model's capacity to generate more natural-like structures. The modification was based on the assumption that it may be preferable for a hydrophobic monomer to have a polar neighbor than to be in direct contact with the polar solvent. The compactness and the segregation criteria were used to compare structures created by the original HP model and by the modified one. An islands' algorithm, a new selection scheme and multiple-points crossover were used to improve the performance of the algorithm. Ten sequences,... Tipo: Info:eu-repo/semantics/article Palavras-chave: HP model; Genetic algorithms; Protein folding. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400023 Registros recuperados: 1 Primeira ... 1 ... Última

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